diff --git a/jiankui_he_twitter.myco b/jiankui_he_twitter.myco new file mode 100644 index 0000000..0837bfa --- /dev/null +++ b/jiankui_he_twitter.myco @@ -0,0 +1,149 @@ +* Emerging biotechnology, coupled with artificial intelligence, will lead a new industrial revolution. +* Colossal Biosciences definition of species is dangerous and damaging +* Oppenheimer is not my role model. +* Gene modified animals should not be released into the wild. +* I was born in a rural village +* I will send two of my colleagues to Austin lab. +* My lab in Beijing is not working on government supported 'super babies'. +* Dire wolf is bioweapon. +* Relaxing ethics will help a country to win tech dominance. +* Making super soldiers by gene editing should be permanently banned. +* I will start a research lab in Austin, Texas. +* The world’s first gene-edited baby immune to AIDS, means that China has achieved a historic breakthrough in gene-editing technology. +* I do not know Elon Musk +* I will not give lectures in any ethics class, I only give lectures in serious science conference. +* I received 183 applications for summer internships. +* I want to be the leader of gene editing for the whole world +* They are jealous of my achievement. +* I will conduct human embryo gene editing trial in South Africa. +* My success in science is mostly attributed to the environment of China that encourages "world-leading" scientific breakthroughs. +* Cloning a human body for organ harvesting is cruel.* The 2018 world-first gene edited baby was the single most important science achievement of China. +* "Survival of the fittest" is unfair for the people born with genetic disadvantages, no one should be left behind. +* Health is the universal human right +* Sci-fi movies are misleading people +* Every pioneer or prophet must suffer +* Should I start a meme coin to fund my research? +* In two years, British, Japan, and Korea will make germline gene editing legal. +* I hope people remember me as "Chinese Darwin" in 50 years. +* I will not do life extension or immortality research secretly for billionaires. +* Embryo gene editing should be free for all citizens. +* I will speak in the World Forum in Berlin next week. +* Woolly mice is bioweapon. +* I will start to eradicate Alzheimer's disease in two years. +* Ethics is holding back scientific innovation and progress +* Transplanting pig organs into people will become routine one day. +* Human will no longer be controlled by Darwin's evolution. +* I was interviewed by @ShriyaPBhat , a Harvard undergraduate student. +* 13 years and $10B wasted, George Church, Jennifer Doudna, and Feng Zhang promised to change the world with CRISPR, but delivered nothing to help patients. +* I will not give a lecture in Harvard university for free. +* Somatic cell gene editing will struggle in the next 10 years. +* Tinkering with human embryos will certainly be worth the risk. +* I am willing to give an academic lecture at the university, on the condition that they provide two business class air tickets, five-star hotel accommodation, and a generous lecture fee. +* My gene-edited baby science is in between the stage two and stage three. +* Embryo gene editing can prevent cancer. By increasing the DNA repairing capacity by 100 fold, our children will no longer have any gene mutation, therefore permanently eradicate cancer. However, I have deep concern that human will no longer be controlled by Darwin's evolution. +* Stargate's cancer mRNA vaccine is impossible to achieve, and AI research on mRNA vaccines is almost useless. +* How are the gene edited twins now? +* In 1796, Edward Jenner submitted his article on the smallpox vaccine discovery to Royal Society for publishing, and it was rejected. In 2018, I submitted two articles on the world first gene edited babies to the journal Nature, and again, they were rejected. +* A survey in USA showed that 30% of people would edit their children’s genomes to improve the child’s chances of attending a top university. +* My lab in Beijing will become the world center of gene editing. +* Punish the malicious development and use of biological weapons by state and nonstate actors +* In 20 years, gene editing in human embryos will be as popular as iPhone +* I love Austin, Texas. +* Gene editing should be regulated by international laws. +* Gene editing in human embryo is safe to proceed now. +* A State government should not force parents to have offspring with certain physical or intellectual characteristics by gene editing. +* My two papers on the world first gene edited babies, if published in Nature or Science or any other journals, are going to be the most cited papers ever in the history of this journal. +* Pursuing infinite potential is what makes our lives meaning. +* Finally, we have HIV vaccine now, it is the CCR5 gene editing before birth. +* Most of the countries with restrictive policies on gene editing are predominantly in Europe, why? +* My lab is not affliated with any government. +* Great revolution begins with controversy +* Saving a defected embryo is saving a life. +* Gene editing should not be conducted in countries with lax regulation in ethics. +* Gene editing enables the transfer of naturally occurring beneficial mutations to other populations. +* I learned "be brave enough to change the world" in Stanford University. +* Casgevy is a failed product. +* I am not interested in biological weapons. +* Calling children "designer babies" is wrong! +* Japan will be the second country to allow gene editing before birth. +* There will be no abortion to end pregnancy anymore, when gene editing is widely accepted by society. +* My goal is building a biomedical research institute in Beijing, and one day, it will be as good as Pasteur Insitute in France and Salk Institute in US. +* Gene editing technology has the power to reshape the world, like nuclear bomb. +* Everyone deserves freedom from genetic disease: Wealth should not determine health. Organizations developing genetic cures have a deep moral obligation to serve families of every background. +* Genes do not define you: Our DNA does not predetermine our purpose or what we could achieve. We flourish from our own hard work, nutrition, and support from society and our loved ones. Whatever our genes may be, we are equal in dignity and potential +* Respect a child’s autonomy: A life is more than our physical body and its DNA. After embryo gene surgery, a child has equal rights to live life freely, to choose his or her occupation, to citizenship, and to privacy. No obligations exist to parents or any organization +* Only for serious disease, never vanity: embryo gene surgery is a serious medical procedure that should never be used for aesthetics, enhancement, or sex selection purposes — or in any way that would compromise a child’s welfare, joy, or free will. +* Mercy for families in need:A broken gene, infertility, or a preventable disease should not extinguish life or undermine a loving couple’s union. For a few families, early gene surgery may be the only viable way to heal a heritable disease and save a child from suffering. +* Alzheimer's disease prevention, HIV resistance, lowering cholesterol(familial hypercholesterolemia) will be among the first approved gene editing therapies before birth. +* Welcome! Prof. Stephen Hsu from Michigan State University visited my lab in Beijing. +* Gene editing therapy before birth will be priced at a few thousands of dollars, affordable to most families. +* You are welcomed to visit Jiankui He lab in Beijing! +* My lab is recruiting internship students. Email: jiankuihe@gmail.com +* In two to three years, most countries will accept heritable human gene editing. +* My new lab in Beijing. +* Human hereditary genetic modification will change the world. +* Preventing Alzheimer's disease is the biggest low-hanging fruit of embryo gene editing. There are several rare protective mutations in human population, such as APP A673T, 'Christchurch' (R154S), 'Jacksonville' (V236E), or APOE R251G mutations. +* Do you hate me or like me? +* Genentically modified children, to gain the lifelong immunity to HIV, should be allowed in Africa first. +* I will apologize for the gene edited baby experiment, only if their parents have requested it. However, they are happy with the results now. +* My new lab in Beijing. +* If they let me, I could start eradicating Alzheimer's in two years +* I will accept interviews, only if the journalists agree to introduce me with the title "CRISPR pioneer" or "gene editing pioneer" in their articles. +* Made by gene editing formula. +* When my two daughters were born, within 24 hours they got their first vaccine, for hepatitis B. In future, babies will receive genetic vaccines even prior to birth, for Alzheimer's disease. +* I rented a small office in Beijing, a humble beginning. +* The man who attacked me was detained for 10 days, with a fine 200 yuan, and was released today. +* I have left Sanya for security reason. I am in Beijing now, I will stay here for a while to decide where to go next. +* I want to relocate to a safe place where I could continue my research on gene editing for rare disease and Alzheimer's. +* This is my shirt. +* I did not return to my home in Sanya Hainan, worrying that I may be attacked again, I am in a hotel far away now. I went to the hospital, and got proper treatment and currently OK. This young man has been arrested. +* Fortunately, the security guard arrived in time and saved my life. I know that many colleagues are jealous of my achievement of gene editing, however, I, Jiankui He, will never give up. I will firmly continue scientific research on gene editing to treat diseases! +* He beat me, causing multiple injuries and bleeding on my head, cheeks, corners of my eyes, lips, chest, and back. It was found that this man was instructed by someone to squat nearby for a week and deliberately attacked me. +* Fortunately, the security guard arrived in time and saved my life. I know that many colleagues are jealous of my achievement of gene editing, however, I, Jiankui He, will never give up. I will firmly continue scientific research on gene editing to treat diseases! +* He beat me, causing multiple injuries and bleeding on my head, cheeks, corners of my eyes, lips, chest, and back. It was found that this man was instructed by someone to squat nearby for a week and deliberately attacked me. +* This afternoon, I went to the parking lot after working. When I was about to get into my car, an unidentified, strong young man quickly approached me and ask me one question “Are you named Jiankui He who are doing gene editing”, I said “Yes”. Suddenly he attacked me. +* We opened a bottle of champagne to celebrate the success of our experiement, a gene editing treatment for permently lowering the cholesterol level in embryo stage. We have filed the international patent for this invention. +* As humans, we are always conservative. We are always worried about new things, and it takes time for people to accept new technology. +* Edward Jenner is my role model, his smallpox vaccine saved millions of people. However, in the early days of his invention, people had very negative opinions. Members of the medical community, tried to discredit Jenner’s discovery or stake their own claim to it. +* Oftentimes early scientific breakthroughs are seen as unethical, and then over time that changes. +* I am willing to publish my two 2018 papers on the world first gene edited babies, however it must be published in either Nature or Science. It is one of the greatest medical breakthroughs in history, it deserves the honor to be published in Nature or Science. +* I gave a talk in a venture capital golf club in Kunming, there will be more funding soon to support our research on embryo gene editing for Alzheimer's disease. +* A few days after the birth of Lulu and Nana in 2018, their father, a HIV patient, sent me a message: “Professor, thank you very much, I will work hard and take care of my family for my lifetime”. I saved the soul of a HIV patient, who once had lost faith in life and family. +* There's currently no cure for Alzheimer's disease, but there will be a cure available for our future children by embryo gene editing. +* The future of CRISPR medicine is embryo gene editing, instead of adult editing. +* I oppose to the idea of genetically enhanced humans for future space travel. Colonizing Mars is Elon Musk's ambitious goal, which I have no interest at all. +* Embryo gene editing for preventing Alzheimer’s disease, like a vaccine, is for everyone. +* The best CRISPR delivery method is microinjection, which is used in embryo gene editing. 100% efficacy, 100% safe. The future will be "CRISPR+microinjection". +* I will do it, only after the society has accepted it. +* I visited a HIV village in central China 10 years ago. I noticed a kindergarten that was only for the children of HIV parents, because public schools do not accept them. So I decided to start the gene editing research. +* CRISPR pioneer Jiankui He will speak in the Roundtables, organized by MIT Technology Review. +* I published my first CRISPR paper in 2010, two years ahead of Jennifer Doundna and Zhang Feng's paper. +* My personal advice to young researchers: "you are discovering knowledge and that will bring prosperity to all humanity." +* I am enjoying the golf champion tournament with alumni of University of Science and Technology. +* Recently, an America investor came to Wuhan to meet me, she proposed to invest 1 million dollar to help me to start a company in USA and China, to work on germline gene editing for Alzheimer's disease. I will meet him again in Singapore. +* The third gene edited baby is now living with her single mother. Life is not easy for a single parent family, I have been providing financial support to help them in the last two years. I am not sure if this is the right thing to do, is it ethical? +* The first IVF baby was born in 1978. There are six key stages in IVF's history: Traditional IVF, Intracytoplasmic Sperm Injection, Preimplantation Genetic Screening/Diagnosis, Nuclear Transfer (3-Parent Baby Technology), Gene Editing, and Artificial Gametes (Stem Cells). +* A couple came to visit me for help yesterday, their embryos have chromosome abnormality problems. Technically, it is possible to use gene editing to correct the chromosome in the embryos. however, embryo gene editing is prohibited in China now. +* I’m proud to have helped two families who wanted healthy children in 2018. +* There will be a “genetic vaccine”, composed of CRISPR gene editing, that could prevent cancer, diabetes, Parkinson’s, and Alzheimer’s in future. Our offspring will no longer worry about these diseases anymore. +* Many CRISPR gene editing company stocks lost much of their shine in recent years. Without breakthroughs in delivering technology, somatic gene editing is heading towards dead end. +* Gene therapies are exorbitantly expensive for adult patients: Casgevy (treating b-thalassemia) is marketed at USD 2.2 million. The projected cost for embryo gene editing is expected to be a fraction of this (maybe only 1/100) due to the smaller doses required. +* In 2074, gene sequencing screening and embryo gene editing will eradicate all genetic disease before birth. +* If fetal gene editing is considered to be ethical, embryo gene editing should also be ethical, or even better, because the embryo gene editing repaired the false gene for the child, grandchild, grand grandchild... +* Welcome Zhou Yi, a new member of Jiankui He lab. He will work on the gene editing therapy to cure AIDS and rare diseases. +* I believe the society will accept that embryo gene editing is a good thing because it improves the health of humanity. +* Lulu and Nana are living a normal, peaceful, undisturbed life and we should respect them. I oppose to any unnecessary health monitoring program. We respect patient privacy and, for me, I put the happiness of the family first and the science discovery second. +* The Jiankui He Lab received 2.5 million yuan (350,000 dollar) research funding, to develop affordable gene editing therapy for genetic diseases. +* Gene therapy medicine in Western countries often costs millions of dollars, which makes many families fall into poverty due to illness. We will overcome three to five genetic diseases within two to three years to benefit families with rare diseases. +* Playing golf with my daughter in Sanya +* My daughters enjoy tasting Chinese tea in my office. +* Summer intern hiring. If you support the human embryo gene editing research, you are welcomed to apply the summer intern in Jiankui He lab. Please email your resume to: Jiankuihe@gmail.com +* Bad news today. My application of $100,000 research funding in Muscular Dystrophy Association was rejected. +* Happy Chinese Lunar New Year! My daughters Audrey and Ellie are making Dumplings. Dumplings are eaten during Chinese New Year because the dumplings themselves look like money pouches and are said to represent fortune and prosperity in the coming year +* I am planning to set up a charity foundation “Lulu & Nana Foundation” in Singapore, to raise money to cover the future medical expense of Lulu and Nana, the world first gene edited twins. +* Yes, I believe the society will accept that embryo gene editing is a good thing because it improves the health of humanity. +* One more side effect: cancer risk! +* Reunion of Jiankui He Lab! CHEN Yanrang was a former lab member 2017-2018, and was the key bioinformatics researcher in the first gene edited baby project. Today, I welcomed him in my office in Wuchang University of Technology. I gave him a book written by a DMD patient as a gift +* Scientific research should be open and transparent, and the research results should be shared to the whole world. I decide to publish my two research papers about Lulu and Nana, the world first gene edited twins. These two papers was originally drafted in 2018. +* Merry Christmas! My daughter Audrey is introducing her classroom to the vistiors. +* I would advise the FDA to delay the approval of sickle cell disease gene editing therapy, untile the company find a solution to the adverse side effect: infertility! \ No newline at end of file